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Sobi is providing this free tool to help you find healthcare providers in your area who may have experience treating chronic ITP. Neither Sobi nor MediFind pay healthcare providers to be listed in this tool and healthcare providers do not pay to be listed in the tool. Just because a healthcare provider is listed in the tool does not mean Sobi endorses their qualifications or recommends their medical care. The search results of healthcare providers are sorted by the distance from the location entered. Choosing a healthcare provider is an important decision requiring careful consideration. Sobi is not responsible for your choice or actions you take because of information provided by the tool.
TREATING CHRONIC ITP
People living with chronic ITP have several treatment options to consider. Learn about those options below and discover more about Doptelet, a type of medicine known as a TPO-RA.
How is chronic ITP treated in adults?
Not all treatments are created equal. There are a few options for treating chronic ITP, such as corticosteroids, intravenous immunoglobulin (IVIG), rituximab, and TPO-RAs—like Doptelet—that offer different benefits. Click on each of these common treatment options to learn how they work.
Corticosteroids are immunosuppressants that work by reducing inflammation and the overall activity of your immune system. For ITP, they are commonly prescribed right after diagnosis and are intended for short-term use to stop your body from destroying platelets.
While steroids can be highly effective, continued use, especially at high doses, may have side effects such as increased weight gain, swelling of the face, sleep problems, and mood disturbances such as irritability. Steroids also come with increased risk of infections, diabetes, cataracts, liver issues, high blood pressure, high blood sugar, osteoporosis, and bone and muscle disorders.
For these reasons, the trusted experts who wrote the current American Society of Hematology (ASH) guidelines recommend limiting steroid treatment to less than 6 weeks.
Ask your doctor for more information about the ASH Guidelines
IVIG is an immune-modulating therapy made of antibodies that can help regulate your immune system. IVIG is a first-line treatment typically used in emergency, short-term situations when platelet counts are severely low. IVIG works by reducing certain immune responses that may be responsible for destroying platelets, but unlike immunosuppressants, it does not weaken the entire immune system.
Rituximab is an immunosuppressant. Like steroids, it works to reduce the overall activity of your immune system to stop your body from destroying platelets. Because rituximab changes how your immune system works, it may be easier for you to get sick or develop other conditions.
If immunosuppressants aren’t working for you, and your platelet counts don’t stay lifted, your doctor may consider a thrombopoietin receptor agonist (TPO-RA), such as Doptelet.
Treating with Doptelet, a medicine called a TPO-RA
Doptelet is a TPO-RA, not an immunosuppressant. TPO-RAs are a type of medication that mimics your body’s natural process of creating platelets. Doptelet can help boost the pathway responsible for making platelets, which adds to the platelets your body is already making. This ultimately increases your overall count.
Doptelet doesn’t require weekly doctor’s appointments for treatment injections or become less effective when you eat certain foods, like ice cream. You can also take Doptelet no matter where you are—just be sure to take it with food and at the same time each day. Work with your doctor to determine a dosing schedule that works best for you.
When you start Doptelet, your doctor will monitor your platelets weekly and then monthly as soon as you reach a platelet count of 50,000 per microliter or more.
Find a chronic ITP specialist near you
One of the most important steps to getting the care you deserve is finding the right hematologist in your area.
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GET ITP TIPSIndication & Important Safety Information
What is DOPTELET (avatrombopag)?
Doptelet is a prescription medicine used to help treat low blood platelet counts in adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough. It is not known if Doptelet is safe or works in children.
Who should not receive Doptelet?
You should not receive Doptelet if you have ever had a blood clot. You should call your healthcare provider or get medical help right away if you have any of the signs or symptoms of a blood clot after taking Doptelet. They can be life-threatening or cause death.
- You Should Know:
- Signs and symptoms of a blood clot could include:
- Swelling, pain, or tenderness in your legs
- Shortness of breath
- Chest pain
- Fast heartbeat
- Stomach pain or tenderness
- Signs and symptoms of a blood clot could include:
Tell your healthcare provider if you are pregnant or breastfeeding, or plan to be while taking Doptelet. It is not known if Doptelet may have unintended side effects for your unborn baby or if Doptelet passes into breast milk. Do not breastfeed while taking Doptelet and for at least 2 weeks after the last dose.
Before taking Doptelet, you should tell your healthcare provider about all your medical conditions and medicines including vitamins, supplements, and herbal remedies.
What are the possible side effects of Doptelet?
For patients with chronic ITP, the most common side effects are headache, fatigue, bruising, nosebleeds, upper respiratory tract infection, joint pain, bleeding gums, purple or red spots on your skin (petechiae), and runny nose.
You Should Know: These are not all of the possible side effects of Doptelet. For more information, ask your healthcare provider or review the Prescribing Information at https://www.doptelet.com/doptelet.pdf.
If you suspect that you have experienced a side effect, call your healthcare provider. You may also report them to the US Food and Drug Administration (FDA) at 1-800-FDA-1088.
For further information, please see full Prescribing Information, including the Patient Information Leaflet.
What is DOPTELET® (avatrombopag)?
Doptelet is a prescription medicine used to help treat low blood platelet counts in adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough. It is not known if Doptelet is safe or works in children.
Who should not receive Doptelet?
You should not receive Doptelet if you have ever had a blood clot. You should call your healthcare provider or get medical help right away if you have any of the signs or symptoms of a blood clot after taking Doptelet. They can be life-threatening or cause death.
- You Should Know:
What is DOPTELET (avatrombopag)?
Doptelet is a prescription medicine used to help treat low blood platelet counts in adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough. It is not known if Doptelet is safe or works in children.
Who should not receive Doptelet?
You should not receive Doptelet if you have ever had a blood clot. You should call your healthcare provider or get medical help right away if you have any of the signs or symptoms of a blood clot after taking Doptelet. They can be life-threatening or cause death.
- You Should Know:
- Signs and symptoms of a blood clot could include:
- Swelling, pain, or tenderness in your legs
- Shortness of breath
- Chest pain
- Fast heartbeat
- Stomach pain or tenderness
- Signs and symptoms of a blood clot could include:
Tell your healthcare provider if you are pregnant or breastfeeding, or plan to be while taking Doptelet. It is not known if Doptelet may have unintended side effects for your unborn baby or if Doptelet passes into breast milk. Do not breastfeed while taking Doptelet and for at least 2 weeks after the last dose.
Before taking Doptelet, you should tell your healthcare provider about all your medical conditions and medicines including vitamins, supplements, and herbal remedies.
What are the possible side effects of Doptelet?
For patients with chronic ITP, the most common side effects are headache, fatigue, bruising, nosebleeds, upper respiratory tract infection, joint pain, bleeding gums, purple or red spots on your skin (petechiae), and runny nose.
You Should Know: These are not all of the possible side effects of Doptelet. For more information, ask your healthcare provider or review the Prescribing Information at https://www.doptelet.com/doptelet.pdf.
If you suspect that you have experienced a side effect, call your healthcare provider. You may also report them to the US Food and Drug Administration (FDA) at 1-800-FDA-1088.
For further information, please see full Prescribing Information, including the Patient Information Leaflet.
