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Sobi is providing this free tool to help you find healthcare providers in your area who may have experience treating chronic ITP. Neither Sobi nor MediFind pay healthcare providers to be listed in this tool and healthcare providers do not pay to be listed in the tool. Just because a healthcare provider is listed in the tool does not mean Sobi endorses their qualifications or recommends their medical care. The search results of healthcare providers are sorted by the distance from the location entered. Choosing a healthcare provider is an important decision requiring careful consideration. Sobi is not responsible for your choice or actions you take because of information provided by the tool.
TREATING CHRONIC ITP
People living with chronic ITP have several treatment options to consider. Learn about those options below and discover more about Doptelet, a type of medicine known as a TPO-RA.
How is chronic ITP treated in adults?
Not all treatments are created equal. There are a few options for treating chronic ITP, such as corticosteroids, intravenous immunoglobulin (IVIG), rituximab, and TPO-RAs—like Doptelet—that offer different benefits. Click on each of these common treatment options to learn how they work.
Corticosteroids are immunosuppressants that work by reducing inflammation and the overall activity of your immune system. For ITP, they are commonly prescribed right after diagnosis and are intended for short-term use to stop your body from destroying platelets.
While steroids can be highly effective, continued use, especially at high doses, may have side effects such as increased weight gain, swelling of the face, sleep problems, and mood disturbances such as irritability. Steroids also come with increased risk of infections, diabetes, cataracts, liver issues, high blood pressure, high blood sugar, osteoporosis, and bone and muscle disorders.
For these reasons, the trusted experts who wrote the current American Society of Hematology (ASH) guidelines recommend limiting steroid treatment to less than 6 weeks.
Ask your doctor for more information about the ASH Guidelines
IVIG is an immune-modulating therapy made of antibodies that can help regulate your immune system. IVIG is a first-line treatment typically used in emergency, short-term situations when platelet counts are severely low. IVIG works by reducing certain immune responses that may be responsible for destroying platelets, but unlike immunosuppressants, it does not weaken the entire immune system.
Rituximab is an immunosuppressant. Like steroids, it works to reduce the overall activity of your immune system to stop your body from destroying platelets. Because rituximab changes how your immune system works, it may be easier for you to get sick or develop other conditions.
If immunosuppressants aren’t working for you, and your platelet counts don’t stay lifted, your doctor may consider a thrombopoietin receptor agonist (TPO-RA), such as Doptelet.
Treating with Doptelet, a medicine called a TPO-RA
Doptelet is a TPO-RA, not an immunosuppressant. TPO-RAs are a type of medication that mimics your body’s natural process of creating platelets. Doptelet can help boost the pathway responsible for making platelets, which adds to the platelets your body is already making. This ultimately increases your overall count.
Doptelet doesn’t require weekly doctor’s appointments for treatment injections or become less effective when you eat certain foods, like ice cream. You can also take Doptelet no matter where you are—just be sure to take it with food and at the same time each day. Work with your doctor to determine a dosing schedule that works best for you.
When you start Doptelet, your doctor will monitor your platelets weekly and then monthly as soon as you reach a platelet count of 50,000 per microliter or more.
Find a chronic ITP specialist near you
One of the most important steps to getting the care you deserve is finding the right hematologist in your area.
Sobi is not responsible for the choices or actions that you or others take because of information provided by this free tool.
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GET ITP TIPSIndication & Important Safety Information
What are DOPTELET (avatrombopag) and DOPTELET Sprinkle (avatrombopag)?
DOPTELET is a prescription medicine used to treat low blood platelet counts in:
- Adults with long-lasting (chronic) liver disease (CLD) who are scheduled to have a medical or dental procedure
- Adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
- Children 1 year and older with persistent or chronic ITP when other treatments have not worked well enough
DOPTELET tablets and DOPTELET Sprinkle are different dosage forms of DOPTELET.
DOPTELET and DOPTELET Sprinkle are not used to make platelet counts normal.
It is not known if DOPTELET or DOPTELET Sprinkle are safe and effective in children younger than 1 year of age.
IMPORTANT SAFETY INFORMATION
Before you take DOPTELET or DOPTELET Sprinkle, tell your doctor about all your medical conditions, including if you:
- Have ever had a blood clot
- Are pregnant or plan to become pregnant. DOPTELET or DOPTELET Sprinkle may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with DOPTELET or DOPTELET Sprinkle
- Are breastfeeding or plan to breastfeed. It is not known if DOPTELET or DOPTELET Sprinkle passes into your breast milk. Do not breastfeed during your treatment with DOPTELET and DOPTELET Sprinkle for at least 2 weeks after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time
Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DOPTELET or DOPTELET Sprinkle may affect the way other medicines work, and other medicines may affect the way DOPTELET or DOPTELET Sprinkle works.
What are the side effects of DOPTELET or DOPTELET Sprinkle?
DOPTELET or DOPTELET Sprinkle may cause serious side effects including blood clots. People with CLD or persistent or chronic ITP and people with certain blood clotting conditions may have an increased risk of developing blood clots. Tell your healthcare provider right away if you get signs and symptoms of a blood clot, including:
- Swelling, pain, or tenderness in your legs
- Shortness of breath
- Chest pain
- Fast heartbeat
- Stomach (abdominal) pain or tenderness
The most common side effects of DOPTELET in adults with CLD are fever, stomach (abdominal) pain, nausea, headache, tiredness, and swelling of hands and feet.
The most common side effects of DOPTELET in adults with chronic ITP are headache, tiredness, bruising, nosebleed, upper respiratory infection, joint pain, bleeding gums, purple or red spots on your skin, and runny nose.
The most common side effects of DOPTELET or DOPTELET Sprinkle in children with persistent or chronic ITP are viral infection, runny nose, cough, fever, and pain in the mouth or throat.
These are not all of the possible side effects of DOPTELET or DOPTELET Sprinkle. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Please see the DOPTELET and DOPTELET Sprinkle full Prescribing Information.
What are DOPTELET (avatrombopag) and DOPTELET Sprinkle (avatrombopag)?
DOPTELET is a prescription medicine used to treat low blood platelet counts in:
- Adults with long-lasting (chronic) liver disease (CLD) who are scheduled to have a medical or dental procedure
- Adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
- Children 1 year and older with persistent or chronic ITP when other treatments have not worked well enough
What are DOPTELET (avatrombopag) and DOPTELET Sprinkle (avatrombopag)?
DOPTELET is a prescription medicine used to treat low blood platelet counts in:
- Adults with long-lasting (chronic) liver disease (CLD) who are scheduled to have a medical or dental procedure
- Adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
- Children 1 year and older with persistent or chronic ITP when other treatments have not worked well enough
DOPTELET tablets and DOPTELET Sprinkle are different dosage forms of DOPTELET.
DOPTELET and DOPTELET Sprinkle are not used to make platelet counts normal.
It is not known if DOPTELET or DOPTELET Sprinkle are safe and effective in children younger than 1 year of age.
IMPORTANT SAFETY INFORMATION
Before you take DOPTELET or DOPTELET Sprinkle, tell your doctor about all your medical conditions, including if you:
- Have ever had a blood clot
- Are pregnant or plan to become pregnant. DOPTELET or DOPTELET Sprinkle may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with DOPTELET or DOPTELET Sprinkle
- Are breastfeeding or plan to breastfeed. It is not known if DOPTELET or DOPTELET Sprinkle passes into your breast milk. Do not breastfeed during your treatment with DOPTELET and DOPTELET Sprinkle for at least 2 weeks after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time
Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DOPTELET or DOPTELET Sprinkle may affect the way other medicines work, and other medicines may affect the way DOPTELET or DOPTELET Sprinkle works.
What are the side effects of DOPTELET or DOPTELET Sprinkle?
DOPTELET or DOPTELET Sprinkle may cause serious side effects including blood clots. People with CLD or persistent or chronic ITP and people with certain blood clotting conditions may have an increased risk of developing blood clots. Tell your healthcare provider right away if you get signs and symptoms of a blood clot, including:
- Swelling, pain, or tenderness in your legs
- Shortness of breath
- Chest pain
- Fast heartbeat
- Stomach (abdominal) pain or tenderness
The most common side effects of DOPTELET in adults with CLD are fever, stomach (abdominal) pain, nausea, headache, tiredness, and swelling of hands and feet.
The most common side effects of DOPTELET in adults with chronic ITP are headache, tiredness, bruising, nosebleed, upper respiratory infection, joint pain, bleeding gums, purple or red spots on your skin, and runny nose.
The most common side effects of DOPTELET or DOPTELET Sprinkle in children with persistent or chronic ITP are viral infection, runny nose, cough, fever, and pain in the mouth or throat.
These are not all of the possible side effects of DOPTELET or DOPTELET Sprinkle. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Please see the DOPTELET and DOPTELET Sprinkle full Prescribing Information.
