GET THE DOPTELET LIFT

Doptelet is a pill that helps your body make more platelets while you compromise less on your personal preferences. That means no doctor’s appointments for treatment injections, no restrictions on what you can eat and when, and more.

Doptelet platelet characters getting ice cream cones at a soft serve stand in carnival scenery

Reach new heights with a platelet count lift that lasts

In the 6-month clinical trial, Doptelet was shown to:

LIFT PLATELETS

Raise platelet counts to 50,000 per microliter or more.

And for some, raise platelet counts to 100,000 per microliter or more. Read more about the results from the clinical trial and follow up review of data below.

ACT FAST

Lift platelet counts in as few as 8 days.

AND LAST

Maintain an increase in platelet counts for an average of 12 total weeks.

  • 49 people were in a 6-month clinical trial for Doptelet (clinical trials for a rare disease usually have smaller sample sizes than non-rare disease trials)
  • During that time, people taking Doptelet were compared with people not taking Doptelet
  • In the 6-month trial, those taking Doptelet were able to keep platelet counts at 50,000 platelets per microliter or higher for an average of 12 total weeks vs 0 weeks for those not taking Doptelet
  • On Day 8 of the trial, 21 out of 32 people taking Doptelet reached at least 50,000 platelets per microliter or more. Those who were not taking Doptelet did not reach 50,000 platelets per microliter
  • A follow-up review of the data from the clinical trial showed that 26 out of 32 patients reached at least 100,000 platelets per microliter at some point during the 6-month trial. The clinical trial was not designed to specifically measure if platelet counts reached 100,000 per microliter. Researchers identified this data in a follow-up review of the clinical trial results. Because this data was reviewed after the clinical trial, it is important to know these results might not be reliable in future clinical trials

What makes Doptelet different?

Doptelet helps make treating chronic ITP more predictable by working with your body
to make more platelets with less compromises.

How Doptelet Works

In this video, you will learn how Doptelet can lift platelet counts.

Play Video: How Doptelet Works

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Play Video: How Doptelet Works

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With Doptelet, there's a chance you may experience side effects

Serious side effects

Doptelet is a TPO-RA, and TPO-RAs have been associated with blood clots. Tell your doctor right away if you have symptoms of a blood clot, including:

  • Swelling, pain, or tenderness in your legs
  • Shortness of breath
  • Chest pain
  • Fast heartbeat
  • Stomach (abdominal) pain or tenderness

Common side effects

You should know that the most common side effects of Doptelet are headache, tiredness, bruising, nosebleed, upper respiratory tract infection, joint pain, gum bleeding, purple or red spots on your skin (petechiae), and runny nose.

These are not all the possible side effects of Doptelet. Talk to your doctor if any side effect bothers you or does not go away.

Surprised doptelet platelet character with glasses

How do I take Doptelet?

Doptelet is a 20-mg pill that must be taken with food. Your doctor will decide how much Doptelet you need to take, and for how
long, based on how your platelet count responds.

Before starting Doptelet, you’ll want to tell your doctor about all of your medical conditions, like if you’ve ever had a blood clot,
are pregnant, or plan to be pregnant.

Doptelet Platelet Character Blowing Bubbles

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Doptelet Platelet Character Blowing Bubbles

Indication & Important Safety Information

What are DOPTELET (avatrombopag) and DOPTELET Sprinkle (avatrombopag)?

DOPTELET is a prescription medicine used to treat low blood platelet counts in:

  • Adults with long-lasting (chronic) liver disease (CLD) who are scheduled to have a medical or dental procedure
  • Adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
  • Children 1 year and older with persistent or chronic ITP when other treatments have not worked well enough

DOPTELET tablets and DOPTELET Sprinkle are different dosage forms of DOPTELET.

DOPTELET and DOPTELET Sprinkle are not used to make platelet counts normal.

It is not known if DOPTELET or DOPTELET Sprinkle are safe and effective in children younger than 1 year of age.

IMPORTANT SAFETY INFORMATION

Before you take DOPTELET or DOPTELET Sprinkle, tell your doctor about all your medical conditions, including if you:

  • Have ever had a blood clot
  • Are pregnant or plan to become pregnant. DOPTELET or DOPTELET Sprinkle may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with DOPTELET or DOPTELET Sprinkle
  • Are breastfeeding or plan to breastfeed. It is not known if DOPTELET or DOPTELET Sprinkle passes into your breast milk. Do not breastfeed during your treatment with DOPTELET and DOPTELET Sprinkle for at least 2 weeks after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DOPTELET or DOPTELET Sprinkle may affect the way other medicines work, and other medicines may affect the way DOPTELET or DOPTELET Sprinkle works.

What are the side effects of DOPTELET or DOPTELET Sprinkle?

DOPTELET or DOPTELET Sprinkle may cause serious side effects including blood clots. People with CLD or persistent or chronic ITP and people with certain blood clotting conditions may have an increased risk of developing blood clots. Tell your healthcare provider right away if you get signs and symptoms of a blood clot, including:

  • Swelling, pain, or tenderness in your legs
  • Shortness of breath
  • Chest pain
  • Fast heartbeat
  • Stomach (abdominal) pain or tenderness

The most common side effects of DOPTELET in adults with CLD are fever, stomach (abdominal) pain, nausea, headache, tiredness, and swelling of hands and feet.

The most common side effects of DOPTELET in adults with chronic ITP are headache, tiredness, bruising, nosebleed, upper respiratory infection, joint pain, bleeding gums, purple or red spots on your skin, and runny nose.

The most common side effects of DOPTELET or DOPTELET Sprinkle in children with persistent or chronic ITP are viral infection, runny nose, cough, fever, and pain in the mouth or throat.

These are not all of the possible side effects of DOPTELET or DOPTELET Sprinkle. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the DOPTELET and DOPTELET Sprinkle full Prescribing Information.

What are DOPTELET (avatrombopag) and DOPTELET Sprinkle (avatrombopag)?

DOPTELET is a prescription medicine used to treat low blood platelet counts in:

  • Adults with long-lasting (chronic) liver disease (CLD) who are scheduled to have a medical or dental procedure
  • Adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
  • Children 1 year and older with persistent or chronic ITP when other treatments have not worked well enough

What are DOPTELET (avatrombopag) and DOPTELET Sprinkle (avatrombopag)?

DOPTELET is a prescription medicine used to treat low blood platelet counts in:

  • Adults with long-lasting (chronic) liver disease (CLD) who are scheduled to have a medical or dental procedure
  • Adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
  • Children 1 year and older with persistent or chronic ITP when other treatments have not worked well enough

DOPTELET tablets and DOPTELET Sprinkle are different dosage forms of DOPTELET.

DOPTELET and DOPTELET Sprinkle are not used to make platelet counts normal.

It is not known if DOPTELET or DOPTELET Sprinkle are safe and effective in children younger than 1 year of age.

IMPORTANT SAFETY INFORMATION

Before you take DOPTELET or DOPTELET Sprinkle, tell your doctor about all your medical conditions, including if you:

  • Have ever had a blood clot
  • Are pregnant or plan to become pregnant. DOPTELET or DOPTELET Sprinkle may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with DOPTELET or DOPTELET Sprinkle
  • Are breastfeeding or plan to breastfeed. It is not known if DOPTELET or DOPTELET Sprinkle passes into your breast milk. Do not breastfeed during your treatment with DOPTELET and DOPTELET Sprinkle for at least 2 weeks after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DOPTELET or DOPTELET Sprinkle may affect the way other medicines work, and other medicines may affect the way DOPTELET or DOPTELET Sprinkle works.

What are the side effects of DOPTELET or DOPTELET Sprinkle?

DOPTELET or DOPTELET Sprinkle may cause serious side effects including blood clots. People with CLD or persistent or chronic ITP and people with certain blood clotting conditions may have an increased risk of developing blood clots. Tell your healthcare provider right away if you get signs and symptoms of a blood clot, including:

  • Swelling, pain, or tenderness in your legs
  • Shortness of breath
  • Chest pain
  • Fast heartbeat
  • Stomach (abdominal) pain or tenderness

The most common side effects of DOPTELET in adults with CLD are fever, stomach (abdominal) pain, nausea, headache, tiredness, and swelling of hands and feet.

The most common side effects of DOPTELET in adults with chronic ITP are headache, tiredness, bruising, nosebleed, upper respiratory infection, joint pain, bleeding gums, purple or red spots on your skin, and runny nose.

The most common side effects of DOPTELET or DOPTELET Sprinkle in children with persistent or chronic ITP are viral infection, runny nose, cough, fever, and pain in the mouth or throat.

These are not all of the possible side effects of DOPTELET or DOPTELET Sprinkle. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the DOPTELET and DOPTELET Sprinkle full Prescribing Information.

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