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WHAT IS CHRONIC ITP?
Immune thrombocytopenia (ITP) is a rare disease, so it’s natural to have lots of questions. Here you’ll find information about what causes ITP, how it’s diagnosed, and how it may be treated.
ITP is a shortage of platelets in your blood
Your immune system’s job is to protect against infection by making antibodies that attack, destroy, and remove foreign substances in the body. ITP is a blood disorder that causes your immune system to produce fewer platelets overall and mistake your platelets for foreign substances and destroy them. This is a serious problem because the main role of platelets is to prevent and stop bleeding in your body.
How is ITP diagnosed?
There’s no specific way to test for ITP—it’s sometimes referred to as a “diagnosis of exclusion.” That means your doctor will try to rule out other possible causes of low platelets, like an underlying illness you may have or any medication you may be taking. If no other cause is found, it may result in a diagnosis of ITP. And if ITP persists for over a year, you may be diagnosed with “chronic ITP.”
ITP diagnostic tests
ITP is a rare autoimmune condition that typically doesn’t have a genetic link—but you should let your doctor know if someone in your family has ITP. For your doctor to determine if you have ITP, they may run a few of these common tests:
- Complete blood count (CBC)
Your doctor will draw a sample of blood and use it to measure your number of blood cells, including your platelet counts
- CBC with differential
A thin layer of your blood—normally taken as part of a CBC—is put on a glass slide and reviewed under a microscope to learn more about the number and shape of your blood cells
- Bone marrow examination
In rare cases, if the other blood tests show that your platelet count is low, your doctor may want to collect a sample of your bone marrow (they’ll numb the area beforehand) to make sure it’s making enough platelets
Learn more about ITP and get answers to the most commonly asked questions.
Find a chronic ITP specialist near you
One of the most important steps to getting the care you deserve is finding the right hematologist in your area.
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GET ITP TIPSIndication & Important Safety Information
What is DOPTELET (avatrombopag)?
Doptelet is a prescription medicine used to help treat low blood platelet counts in adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough. It is not known if Doptelet is safe or works in children.
Who should not receive Doptelet?
You should not receive Doptelet if you have ever had a blood clot. You should call your healthcare provider or get medical help right away if you have any of the signs or symptoms of a blood clot after taking Doptelet. They can be life-threatening or cause death.
- You Should Know:
- Signs and symptoms of a blood clot could include:
- Swelling, pain, or tenderness in your legs
- Shortness of breath
- Chest pain
- Fast heartbeat
- Stomach pain or tenderness
- Signs and symptoms of a blood clot could include:
Tell your healthcare provider if you are pregnant or breastfeeding, or plan to be while taking Doptelet. It is not known if Doptelet may have unintended side effects for your unborn baby or if Doptelet passes into breast milk. Do not breastfeed while taking Doptelet and for at least 2 weeks after the last dose.
Before taking Doptelet, you should tell your healthcare provider about all your medical conditions and medicines including vitamins, supplements, and herbal remedies.
What are the possible side effects of Doptelet?
For patients with chronic ITP, the most common side effects are headache, fatigue, bruising, nosebleeds, upper respiratory tract infection, joint pain, bleeding gums, purple or red spots on your skin (petechiae), and runny nose.
You Should Know: These are not all of the possible side effects of Doptelet. For more information, ask your healthcare provider or review the Prescribing Information at https://www.doptelet.com/doptelet.pdf.
If you suspect that you have experienced a side effect, call your healthcare provider. You may also report them to the US Food and Drug Administration (FDA) at 1-800-FDA-1088.
For further information, please see full Prescribing Information, including the Patient Information Leaflet.
What is DOPTELET® (avatrombopag)?
Doptelet is a prescription medicine used to help treat low blood platelet counts in adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough. It is not known if Doptelet is safe or works in children.
Who should not receive Doptelet?
You should not receive Doptelet if you have ever had a blood clot. You should call your healthcare provider or get medical help right away if you have any of the signs or symptoms of a blood clot after taking Doptelet. They can be life-threatening or cause death.
- You Should Know:
What is DOPTELET (avatrombopag)?
Doptelet is a prescription medicine used to help treat low blood platelet counts in adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough. It is not known if Doptelet is safe or works in children.
Who should not receive Doptelet?
You should not receive Doptelet if you have ever had a blood clot. You should call your healthcare provider or get medical help right away if you have any of the signs or symptoms of a blood clot after taking Doptelet. They can be life-threatening or cause death.
- You Should Know:
- Signs and symptoms of a blood clot could include:
- Swelling, pain, or tenderness in your legs
- Shortness of breath
- Chest pain
- Fast heartbeat
- Stomach pain or tenderness
- Signs and symptoms of a blood clot could include:
Tell your healthcare provider if you are pregnant or breastfeeding, or plan to be while taking Doptelet. It is not known if Doptelet may have unintended side effects for your unborn baby or if Doptelet passes into breast milk. Do not breastfeed while taking Doptelet and for at least 2 weeks after the last dose.
Before taking Doptelet, you should tell your healthcare provider about all your medical conditions and medicines including vitamins, supplements, and herbal remedies.
What are the possible side effects of Doptelet?
For patients with chronic ITP, the most common side effects are headache, fatigue, bruising, nosebleeds, upper respiratory tract infection, joint pain, bleeding gums, purple or red spots on your skin (petechiae), and runny nose.
You Should Know: These are not all of the possible side effects of Doptelet. For more information, ask your healthcare provider or review the Prescribing Information at https://www.doptelet.com/doptelet.pdf.
If you suspect that you have experienced a side effect, call your healthcare provider. You may also report them to the US Food and Drug Administration (FDA) at 1-800-FDA-1088.
For further information, please see full Prescribing Information, including the Patient Information Leaflet.
