WHAT IS CHRONIC ITP?

Immune thrombocytopenia (ITP) is a rare disease, so it’s natural to have lots of questions. Here you’ll find information about what causes ITP, how it’s diagnosed, and how it may be treated.

Doptelet platelet characters holding colorful balloons in carnival scenery

ITP is a shortage of platelets in your blood

Your immune system’s job is to protect against infection by making antibodies that attack, destroy, and remove foreign substances in the body. ITP is a blood disorder that causes your immune system to produce fewer platelets overall and mistake your platelets for foreign substances and destroy them. This is a serious problem because the main role of platelets is to prevent and stop bleeding in your body.

How is ITP diagnosed?

Doptelet platelet characters getting ice cream cones at a soft serve stand

There’s no specific way to test for ITP—it’s sometimes referred to as a “diagnosis of exclusion.” That means your doctor will try to rule out other possible causes of low platelets, like an underlying illness you may have or any medication you may be taking. If no other cause is found, it may result in a diagnosis of ITP. And if ITP persists for over a year, you may be diagnosed with “chronic ITP.”

Doptelet platelet characters getting ice cream cones at a soft serve stand

ITP diagnostic tests

ITP is a rare autoimmune condition that typically doesn’t have a genetic link—but you should let your doctor know if someone in your family has ITP. For your doctor to determine if you have ITP, they may run a few of these common tests:

  • Complete blood count (CBC)
    Your doctor will draw a sample of blood and use it to measure your number of blood cells, including your platelet counts
  • CBC with differential
    A thin layer of your blood—normally taken as part of a CBC—is put on a glass slide and reviewed under a microscope to learn more about the number and shape of your blood cells
  • Bone marrow examination
    In rare cases, if the other blood tests show that your platelet count is low, your doctor may want to collect a sample of your bone marrow (they’ll numb the area beforehand) to make sure it’s making enough platelets

Learn more about ITP and get answers to the most commonly asked questions.

Find a chronic ITP specialist near you

One of the most important steps to getting the care you deserve is finding the right hematologist in your area.

Sobi is not responsible for the choices or actions that you or others take because of information provided by this free tool.

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Indication & Important Safety Information

What are DOPTELET (avatrombopag) and DOPTELET Sprinkle (avatrombopag)?

DOPTELET is a prescription medicine used to treat low blood platelet counts in:

  • Adults with long-lasting (chronic) liver disease (CLD) who are scheduled to have a medical or dental procedure
  • Adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
  • Children 1 year and older with persistent or chronic ITP when other treatments have not worked well enough

DOPTELET tablets and DOPTELET Sprinkle are different dosage forms of DOPTELET.

DOPTELET and DOPTELET Sprinkle are not used to make platelet counts normal.

It is not known if DOPTELET or DOPTELET Sprinkle are safe and effective in children younger than 1 year of age.

IMPORTANT SAFETY INFORMATION

Before you take DOPTELET or DOPTELET Sprinkle, tell your doctor about all your medical conditions, including if you:

  • Have ever had a blood clot
  • Are pregnant or plan to become pregnant. DOPTELET or DOPTELET Sprinkle may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with DOPTELET or DOPTELET Sprinkle
  • Are breastfeeding or plan to breastfeed. It is not known if DOPTELET or DOPTELET Sprinkle passes into your breast milk. Do not breastfeed during your treatment with DOPTELET and DOPTELET Sprinkle for at least 2 weeks after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DOPTELET or DOPTELET Sprinkle may affect the way other medicines work, and other medicines may affect the way DOPTELET or DOPTELET Sprinkle works.

What are the side effects of DOPTELET or DOPTELET Sprinkle?

DOPTELET or DOPTELET Sprinkle may cause serious side effects including blood clots. People with CLD or persistent or chronic ITP and people with certain blood clotting conditions may have an increased risk of developing blood clots. Tell your healthcare provider right away if you get signs and symptoms of a blood clot, including:

  • Swelling, pain, or tenderness in your legs
  • Shortness of breath
  • Chest pain
  • Fast heartbeat
  • Stomach (abdominal) pain or tenderness

The most common side effects of DOPTELET in adults with CLD are fever, stomach (abdominal) pain, nausea, headache, tiredness, and swelling of hands and feet.

The most common side effects of DOPTELET in adults with chronic ITP are headache, tiredness, bruising, nosebleed, upper respiratory infection, joint pain, bleeding gums, purple or red spots on your skin, and runny nose.

The most common side effects of DOPTELET or DOPTELET Sprinkle in children with persistent or chronic ITP are viral infection, runny nose, cough, fever, and pain in the mouth or throat.

These are not all of the possible side effects of DOPTELET or DOPTELET Sprinkle. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the DOPTELET and DOPTELET Sprinkle full Prescribing Information.

What are DOPTELET (avatrombopag) and DOPTELET Sprinkle (avatrombopag)?

DOPTELET is a prescription medicine used to treat low blood platelet counts in:

  • Adults with long-lasting (chronic) liver disease (CLD) who are scheduled to have a medical or dental procedure
  • Adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
  • Children 1 year and older with persistent or chronic ITP when other treatments have not worked well enough

What are DOPTELET (avatrombopag) and DOPTELET Sprinkle (avatrombopag)?

DOPTELET is a prescription medicine used to treat low blood platelet counts in:

  • Adults with long-lasting (chronic) liver disease (CLD) who are scheduled to have a medical or dental procedure
  • Adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
  • Children 1 year and older with persistent or chronic ITP when other treatments have not worked well enough

DOPTELET tablets and DOPTELET Sprinkle are different dosage forms of DOPTELET.

DOPTELET and DOPTELET Sprinkle are not used to make platelet counts normal.

It is not known if DOPTELET or DOPTELET Sprinkle are safe and effective in children younger than 1 year of age.

IMPORTANT SAFETY INFORMATION

Before you take DOPTELET or DOPTELET Sprinkle, tell your doctor about all your medical conditions, including if you:

  • Have ever had a blood clot
  • Are pregnant or plan to become pregnant. DOPTELET or DOPTELET Sprinkle may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with DOPTELET or DOPTELET Sprinkle
  • Are breastfeeding or plan to breastfeed. It is not known if DOPTELET or DOPTELET Sprinkle passes into your breast milk. Do not breastfeed during your treatment with DOPTELET and DOPTELET Sprinkle for at least 2 weeks after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DOPTELET or DOPTELET Sprinkle may affect the way other medicines work, and other medicines may affect the way DOPTELET or DOPTELET Sprinkle works.

What are the side effects of DOPTELET or DOPTELET Sprinkle?

DOPTELET or DOPTELET Sprinkle may cause serious side effects including blood clots. People with CLD or persistent or chronic ITP and people with certain blood clotting conditions may have an increased risk of developing blood clots. Tell your healthcare provider right away if you get signs and symptoms of a blood clot, including:

  • Swelling, pain, or tenderness in your legs
  • Shortness of breath
  • Chest pain
  • Fast heartbeat
  • Stomach (abdominal) pain or tenderness

The most common side effects of DOPTELET in adults with CLD are fever, stomach (abdominal) pain, nausea, headache, tiredness, and swelling of hands and feet.

The most common side effects of DOPTELET in adults with chronic ITP are headache, tiredness, bruising, nosebleed, upper respiratory infection, joint pain, bleeding gums, purple or red spots on your skin, and runny nose.

The most common side effects of DOPTELET or DOPTELET Sprinkle in children with persistent or chronic ITP are viral infection, runny nose, cough, fever, and pain in the mouth or throat.

These are not all of the possible side effects of DOPTELET or DOPTELET Sprinkle. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the DOPTELET and DOPTELET Sprinkle full Prescribing Information.

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