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About Doptelet
Doptelet is a TPO-RA that helps lift your low platelet counts while keeping some of your personal preferences in mind. Think: Chronic ITP treatment with no food-type restrictions, no doctor’s appointments for treatment injections, and more.
In a 6-month clinical trial, Doptelet was shown to:
Keep patients’ platelets lifted at 50,000 platelets per microliter or higher…
for an average of 12 total weeks…
and lifted platelet counts in as few as 8 days!
Your treatment should lift your platelet count fast and help make it last while keeping some of your personal preferences in mind
Doptelet works with your body to help you make more platelets with less compromise
No treatment injections
Doptelet isn’t a steroid—it’s a TPO-RA (thrombopoietin receptor agonist) pill that can be taken anywhere.
Fits your schedule
You can take it on your ideal schedule, as long as you take it at the same time each day.
No food-type restrictions
Unlike some other TPO-RAs, there are no limits on your favorite foods (especially ones with calcium, iron, aluminum, magnesium, selenium, and zinc in them). #FoodRequired
No liver monitoring
Doptelet doesn’t require additional liver-function monitoring because in clinical trials it was not shown to lead to liver damage (aka “hepatotoxicity” in medical terms).
No eye exams
Doptelet can be used in people with cataracts. No eye exams are required before starting and during treatment with Doptelet.
Dopteller Diaries:
A Doctor’s Guide to Exploring Treatment Options
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Dopteller Diaries:
A Doctor’s Guide to Exploring Treatment Options
Dr. Van Doren is a real doctor, but not Tammy’s doctor.
Real patients. Real results.
- 49 patients were in a 6-month clinical trial for Doptelet (clinical trials for a rare disease usually have smaller sample sizes than non-rare disease trials)
- During that time, patients taking Doptelet were compared with patients not taking Doptelet
- In a 6-month trial, those taking Doptelet were able to keep platelet counts at 50,000 platelets per microliter or higher for an average of 12 total weeks vs 0 weeks for those not taking Doptelet
- On Day 8 of the trial, 21 out of 32 patients taking Doptelet reached at least 50,000 platelets per microliter or more
- Those who were not taking Doptelet did not reach 50,000 platelets per microliter
Like all medicines, there’s a chance you may experience side effects with Doptelet
Common side effects
The most common side effects of Doptelet are:
- Headache
- Tiredness
- Bruising
- Nosebleed
- Upper respiratory tract infection
- Joint pain
- Gum bleeding
- Purple or red spots on your skin
- Runny nose
Serious side effects
Doptelet is a TPO-RA and TPO-RAs have been associated with blood clots. Tell your doctor right away if you have symptoms of a blood clot, including:
- Swelling, pain, or tenderness in your legs
- Shortness of breath
- Chest pain
- Fast heartbeat
- Stomach (abdominal) pain or tenderness
These are not all the possible side effects of Doptelet. Talk to your doctor if any side effect bothers you or does not go away.
Feel informed before talking to your doctor
It’s important to understand every detail of treatment before starting the conversation about Doptelet with your doctor, so you can feel confident voicing your preferences and have more collaborative discussions.
How can I get Doptelet?
Doptelet Connect is a support program that can help you get and start on Doptelet. Its dedicated Case Managers will work with you and your doctor to find a pharmacy that can fill your prescription.
Here’s how it works:
1.
Your doctor sends your prescription to Doptelet Connect
2.
Dedicated Case Managers can help:
- Research your individual coverage for Doptelet
- Coordinate with an eligible pharmacy to fill your prescription
- Connect with you to identify financial assistance options, if needed. You must meet eligibility criteria
- Research your individual coverage for Doptelet
- Coordinate with an eligible pharmacy to fill your prescription
- Connect with you to identify financial assistance options, if needed. You must meet eligibility criteria
3.
When your doctor prescribes Doptelet, a pharmacy will contact you. Please answer or return their call as soon as you can.
Ask your doctor how you can get a free trial of Doptelet to see if it’s right for you.
How do I take Doptelet?
Doptelet is a 20-mg pill that must be taken with food. Your doctor will decide how much Doptelet you need to take, and for how long, based on your unique platelet count.
You and your doctor should work together to set your treatment goals on Doptelet.
If you miss your dose of Doptelet, take it as soon as you remember. Don’t take 2 doses at once to make up for missing the 1. You should take your next dose at your usual time.
If you think you’ve taken more Doptelet than you were prescribed, call your doctor or go to the nearest emergency room right away.
Everyone’s treatment goals are different, so it’s important to keep taking Doptelet exactly as your doctor prescribed, based on the treatment plan you agreed on together. If you have questions about how long you’ll be on Doptelet, talk to your doctor or care team—they’re there to help.
Talking to your doctor is the best way to see if Doptelet is a good fit for you
Sounds like Doptelet might be able to help manage your platelet counts and meet your treatment needs? The next step is to start the discussion with your doctor. Don’t worry, we have a list of conversation-starters and tips from Tammy—a real patient—to help you prepare.
Got a story to share about your chronic ITP?
Interested in joining Tammy (that’s her up there^) as a Doptelet patient ambassador?
IMPORTANT SAFETY INFORMATION
What is DOPTELET® (avatrombopag) [dop-TEL-et]?
DOPTELET is a prescription medicine used to treat low blood platelet counts in adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
Doptelet is used to help raise platelet counts in adults with chronic ITP, but it is not used to make platelet counts normal in these patients. It is not known if DOPTELET is safe and effective in children.
IMPORTANT SAFETY INFORMATION
Before taking DOPTELET, tell your healthcare provider about all your medical conditions, including if you:
- have ever had a blood clot.
- are pregnant or plan to become pregnant. DOPTELET may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with DOPTELET.
- are breastfeeding or plan to breastfeed. It is not known if DOPTELET passes into your breast milk. Do not breastfeed during your treatment with DOPTELET and for at least 2 weeks after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time.
Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DOPTELET may affect the way other medicines work, and other medicines may affect the way DOPTELET works.
What are the possible side effects of DOPTELET?
DOPTELET may cause serious side effects, including blood clots. People with chronic immune thrombocytopenia and people with certain blood clotting conditions may have increased risk of developing blood clots. Tell your healthcare provider right away if you have signs and symptoms of a blood clot, including:
- swelling, pain, or tenderness in your legs
- shortness of breath
- chest pain
- fast heartbeat
- stomach (abdominal) pain or tenderness
The most common side effects of DOPTELET when used to treat low blood platelet counts in adults with chronic immune thrombocytopenia (ITP) are:
- headache
- tiredness
- bruising
- nosebleed
- upper respiratory tract infection
- joint pain
- bleeding gums
- purple or red spots on your skin
- runny nose
These are not all the possible side effects of DOPTELET. Call your doctor for medical advice about side effects. You are encouraged to report side effects to FDA at 1-800-FDA-1088.
For further information, please see full Prescribing Information, including the Patient Information Leaflet.
What is DOPTELET® (avatrombopag) [dop-TEL-et]?
What is DOPTELET® (avatrombopag) [dop-TEL-et]?
DOPTELET is a prescription medicine used to treat low blood platelet counts in adults with chronic immune thrombocytopenia (ITP) when other treatments have not worked well enough.
Doptelet is used to help raise platelet counts in adults with chronic ITP, but it is not used to make platelet counts normal in these patients. It is not known if DOPTELET is safe and effective in children.
IMPORTANT SAFETY INFORMATION
Before taking DOPTELET, tell your healthcare provider about all your medical conditions, including if you:
- have ever had a blood clot.
- are pregnant or plan to become pregnant. DOPTELET may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with DOPTELET.
- are breastfeeding or plan to breastfeed. It is not known if DOPTELET passes into your breast milk. Do not breastfeed during your treatment with DOPTELET and for at least 2 weeks after the last dose. Talk to your healthcare provider about the best way to feed your baby during this time.
Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DOPTELET may affect the way other medicines work, and other medicines may affect the way DOPTELET works.
What are the possible side effects of DOPTELET?
DOPTELET may cause serious side effects, including blood clots. People with chronic immune thrombocytopenia and people with certain blood clotting conditions may have increased risk of developing blood clots. Tell your healthcare provider right away if you have signs and symptoms of a blood clot, including:
- swelling, pain, or tenderness in your legs
- shortness of breath
- chest pain
- fast heartbeat
- stomach (abdominal) pain or tenderness
The most common side effects of DOPTELET when used to treat low blood platelet counts in adults with chronic immune thrombocytopenia (ITP) are:
- headache
- tiredness
- bruising
- nosebleed
- upper respiratory tract infection
- joint pain
- bleeding gums
- purple or red spots on your skin
- runny nose
These are not all the possible side effects of DOPTELET. Call your doctor for medical advice about side effects. You are encouraged to report side effects to FDA at 1-800-FDA-1088.
For further information, please see full Prescribing Information, including the Patient Information Leaflet.
